Tuesday, Dec 13th

 
   
8:30-8:45 am Jonathan Crowston, Franz Grus & Keith Martin
  Welcome and Introduction
   
08:45 - 10:00 am Session I: Neural replacement and regeneration
  [Moderators: Martin, Fischer]
8:45 - 9:10 Alice Pebay
  Human pluripotent stem cells for retinal disease
09:10 - 9:35 Elena Vecino
  Microtubule polymerisation during RGC axon regeneration
9:35 - 10:00 Ann Logan
  siRNA and regeneration
   
30 min tea break
 
   
10:30 - 11:55 am Session II: Modulating neuronal function
  [Moderators: Mackey, Bell]
10:30 - 10:55 Jessica Kwok
  Perineural net mediated neuroplasticity
10:55 - 11:20 Steven Petrou 
  Taming the excitable cell
11:20-11:45 Yves Barde
  Neurotrophins in development and disease
11:45 - 11:55 George Kong
  Improvement of Visual Field following successful Trabeculectomy is related to Preoperative Mean Deviation
   
lunch and afternoon break
 
   
05:30 -  6:40 pm Session III: Gene Therapy 
  [Moderators: Crowston, Pebay]
5:30 - 5:55 David Mackey
  Gene based therapies for LHON hype or hope
5:55 - 6:20 Andrew Osborne
  Targetting RGC with gene therapy
6:20 - 6:30 Kim Lemmens
  Dendritic remodeling as fuel for axonal regeneration in the injured zebrafish retinotectal system? Primary insights from MMP inhibitory research
6:30 -6:40 Lien Andries
  MMP-2 as a modulator of dendritic and axonal responses in the injured mammalian central nervous system
   

Wednesday, Dec 14th

 
   
08:30 - 10:05 am Session IV: Neuroinflammation and glia
  [Moderators: Karadottir, Williams]
8:30 - 8:55 Kristian Franze 
  Microglial mechanics
8:55 - 9:20 Crawford Downs
  Astrocyte and biomechanics
9:20 - 9:45 James Tribble
  Reconstruction of RGCs in human glaucomatous tissue using serial block face electron microscopy
9:45 - 9:55 Vanessa Beutgen
  Profiling of autoantibodies in sera of patients with POAG by serological proteome analysis (SERPA)
9:55 - 10:05 Carsten Schmelter
  Peptides of the variable region of antibodies as potential biomarker candidates in primary open-angle glaucoma (POAG).
   
20 min tea break
 
   
10:25 - 12:05 Session V: Mitochondria, stress and power
  [Moderators: Levkovitch, Morgan]
10:25 - 10:50 Christian Behl 
  Autophagy - a source of power
10:50 - 11:15 Pete Williams
  NAD supply critically modulates mitochondrial vulnerability and neurodegeneration in aged mice
11:15 - 11:40 Robert Casson
  Oxidative Stress at the Optic Nerve Head in Experimental Glaucoma
11:40 - 11:55 Julia Teister
  Fluorescence lifetime imaging of the ocular fundus in healthy and diseased rats
11:55 - 12:05 Fabian Anders
  Intravitreal injection of β-crystallin B2 improves retinal ganglion cell survival in an experimental animal model of glaucoma
   
lunch and afternoon break
 
   
05:30 -  7:05 pm Session VI: Regeneration and immunosenescence
  [Moderators: Vecino, Logan]
5:30 - 5:55 Dietmar Fischer
  Role of GSK3 activity in optic nerve regeneration
5:55 - 6:20 Rossella Russo
  Changing the fate of retinal ganglion cells following retinal ischemia: is autophagy the way?
6:20 - 6:45 Richard Eva
  "Axonal transport as a target for enhancing
CNS regeneration"
6:45 - 7:05 Anton Hommer
  Hurdles on the way from science to the patient
   

Thursday, Dec 15th

 
   
08:30 - 10:25 am Session VII: Neurotrophins, neuroprotection, repair
  [Moderators: Downs , Inatani]
8:30 - 8:55 James Morgan
  Protecting dendrites
8:55 - 9:20 Flora Hui
  Optimising ERG for monitoring  inner retinal function-moving from the lab  into the clinic
9:20 - 9:45 Thora Karadottir
  Regulation of remyelination
9:45 - 10:10 Bjoern Neumann
  remyelination of regenerating axons
10:10 - 10:25 Katharina Bell
  Neurotrophins involved in neuroprotective antibody effect
   
25 min tea break
 
   
10:50 - 12:05 am Session VIII: Advances in imaging
  [Moderators: Grus, Morgan]
10:50 - 11:15 Xavier Hadoux
  the promise of hyperspectral imaging
11:15 - 11:40 Andy McNaught
  Imaging oxygen levels in the retina
11:40 - 12:05 Masaru Inatani
  Mitochondrial trafficking
   
lunch and afternoon break
 
   
05:30 - 6:15 pm Session IX: Translation and commercialization
  [Moderators: Petrou, Osborne]
5:30 - 5:55 Stefano Gandolfi
  Current unmet clinical challenges
5:55 - 6:05 Kota Sato
  The neuroprotective effect of latanoprost after optic nerve transection acts via OATP2B1-mediated klotho fragmentation
6:05 - 6:15 Elena Ioyleva
  Opportunities OCT to study the asymmetry of optic disc changes depending on the duration of multiple sclerosis.